Ketogenic diet can slow ageing, study suggests

Ketogenic diet can slow ageing, study suggests

Ketogenic diet can slow ageing, study suggests

The low-carb, high-fat diet might also prevent a host of diseases, the research suggests. 

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New research from the Gladstone Institute for Virology and Immunology in San Francisco, published in the journal Science suggests that the Ketogenic Diet could slow down the ageing process.

The diet, which is based on a low-carb, high-fat eating plan, shot to popularity in 2017, with celebrities espousing its benefits and popular gym franchise F45 recommending it to clients in order to optimize weight loss, detox and build muscle.

But new data suggests that, beyond these capabilities, the diet “may prevent age-related conditions, such as heart disease, Alzheimer's and even cancer,” per a report on The Daily Mail.

The reason why is because the diet – as its name suggests – puts the body in a state of ketosis (or starvation) which triggers the release of chemical β-hydroxybutyrate (βOHB), “which protects cells from 'internal stress.'”

Internal stress, the research finds, is linked to a certain type of genetic cell damage that causes ageing, and a host of other adverse health conditions.

Dr Katerina Akassoglou, who helmed the study said, “the findings could be relevant for a wide range of neurological conditions, such as Alzheimer's, Parkinson's, autism and traumatic brain injury.

“[These] diseases afflict millions and there are few treatment options.”

To reach this conclusion, Dr Akassoglou and her team limited how many calories mice consumed in order to trigger a rise in their βOHB levels, simultaneously “blocking the effects of the enzyme histone deacetylases (HDACs).”

This activated certain genes, which protected cells from internal stress.

According to The Daily Mail, the study’s co-author Dr Eric Verdin said, “over the years, studies have found that restricting calories slows aging and increases longevity, however, the mechanism of this effect has remained elusive.

“Here, we find that βOHB, the body's major source of energy during exercise or fasting, blocks a class of enzymes that would otherwise promote stress, thus protecting cells from aging.”

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