Ibuprofen linked to male infertility, study suggests

Ibuprofen linked to male infertility, study suggests

Ibuprofen linked to male infertility, study suggests

Research shows the common painkiller may put men at risk of low sperm production over time.

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While it relieves pain, ibuprofen may also reduce male fertility, according to a small but compelling new study.

The research, published in the journal Proceedings of the National Academy of Sciences, followed 31 healthy young men.

Participants filled out questionnaires about their general health and gave blood samples. Men were then divided — 14 in an ibuprofen group, 17 in a placebo group – and the ibuprofen participants given 600 mg twice a day, or the equivalent of three tablets.

Within two weeks of having the twice daily dose, the 18 to 35-year-olds who took part in the study developed a disorder called “compensated hypogonadism”. The condition occurs when the body has to boost levels of testosterone because normal production in the testes has fallen.

Doctors in Copenhagen who led the study said that while the disorder was mild and temporary in the study participants, they feared it could become permanent in long-term users of the popular painkiller.

“Our immediate concern is for the fertility of men who use these drugs for a long time,” said David Møbjerg Kristensen at the University of Copenhagen.

“These compounds are good painkillers, but a certain amount of people in society use them without thinking of them as proper medicines.”

The finding comes after repeated warnings from other researchers that ibuprofen can raise the risk of heart attacks in the general population and cause medical problems for pregnant women and their babies, including a more than doubling of the risk of miscarriage.

The new IVF breakthrough1:18

Australian fertility specialists Genea have developed a new system that significantly reduces how often an embryo is disturbed during its developing – leading to a much higher number of healthy embryos per IVF attempt.


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